Suppose you visit the Dalai Lama in Dharamsala, India (elevation 1460 m), and you begin to ponder the “big questions,” such as “ is the fractional saturation of the Dalai

Suppose you visit the Dalai Lama in Dharamsala, India (elevation 1460 m), and you begin to ponder the “big questions,” such as “ is the fractional saturation of the Dalai Lama’s hemoglobin?” (a) Assuming the Dalai Lama’s hemoglobin has a ll coefficient = 3.2, and a P 50 = 31 mm Hg, calculate the change in fractional O 2 saturation of his hemoglobin going from his lungs (where P O2 = 85 mm Hg) to his capillaries (where P O2 = 25 mm Hg). (b) Why do you suppose the Dalai Lama’s hemoglobin has a P 50 higher than normal (where “normal” = 27 mm Hg)?

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